Configuration C

[mysqld]
socket=/path/to/mysql.sock
datadir=/var/lib/mysql
skip-locking
skip-innodb
# Enable query caching for vast improvement and it may be all you need to tweak.
query_cache_type=1
query_cache_limit=1M
query_cache_size=32M
# max_connections=500
# Reduced to 200 as memory will not be enough for 500 connections.
# memory=key_buffer+(sort_buffer_size+read_buffer_size)*max_connections
# which is now: 64 + (1 + 1) * 200 = 464 MB
#interactive_timeout=180
interactive_timeout=100
#wait_timeout=180
#wait_timeout=100
# Reduced wait_timeout to prevent idle clients holding connections.
#wait_timeout=30
wait_timeout=15
connect_timeout=10
# max_connect_errors is set to 10 by default
#max_connect_errors=10
# Checked opened tables and adjusted accordingly after running for a while.
table_cache=512
#tmp_table_size=32M by default
#thread_cache=128
# Reduced it to 32 to prevent memory hogging. 
thread_cache=32
# key_buffer=258M
# Reduced it by checking current size of *.MYI files.
key_buffer=128M
# Commented out the buffer sizes and keeping the default.
# sort_buffer_size=2M by default.
sort_buffer_size=1M
# read_buffer_size=128K by default.
read_buffer_size=1M
# read_rnd_buffer_size=256K by default.
read_rnd_buffer_size=1M
# myisam_sort_buffer_size=8M by default.
#myisam_sort_buffer_size=64M
# thread_concurrency = 2 * (no. of CPU)
thread_concurrency=2
# log slow queries is a must. Many queries that take more than 2 seconds. 
# If so, then your tables need enhancement.
log_slow_queries=/var/log/mysqld.slow.log
long_query_time=2

[mysql.server]
user=mysql
basedir=/var/lib

[safe_mysqld]
err-log=/var/log/mysqld.log
pid-file=/var/run/mysqld/mysqld.pid
open_files_limit=8192

[mysqldump]
quick
max_allowed_packet=16M

[mysql]
no-auto-rehash
# Remove the next comment character if you are not familiar with SQL
#safe-updates

[isamchk]
key_buffer=64M
sort_buffer=64M
read_buffer=16M
write_buffer=16M

[myisamchk]
key_buffer=64M
sort_buffer=64M
read_buffer=16M
write_buffer=16M

[mysqlhotcopy]
interactive-timeout 

[client]
socket=/path/to/mysql.sock